Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070912 | 0.89 | NPC1 (0.41) | ALDH1A1KMT2AKDM4EGAANPC1 | |
| SCHEMBL10680765 | 0.89 | NPC1 (0.41) | ALDH1A1KMT2AKDM4EGAANPC1 | |
| SCHEMBL30967800 | 0.84 | KMT2A (0.44) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22071024 | 0.82 | TP53 (0.44) | ALDH1A1KMT2AKDM4EGAANPC1 | |
| SCHEMBL31537552 | 0.79 | KMT2A (0.49) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL15823733 | 0.79 | KDM4E (0.49) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL794501 | 0.79 | KMT2A (0.49) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL10529585 | 0.78 | CYP4F2 (0.54) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL9370726 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EGAANPC1 | |
| SCHEMBL16836044 | 0.78 | KDM4E (0.56) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135177-B1 | BENZOCYCLOALKANE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |
| US-4777257-A | CARDIOVASCULAR DISORDERS | DAIICHI SEIYAKU CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| US-4665188-A | Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecarboxylic acids or corresponding idan-carboxylic acids which are thromboxane A2 | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0135177-A2 | Benzocycloalkane derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-03-27 | — | — | EP | disclosed |