Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181224 | 0.92 | ACHE (0.54) | ACHEHRH2HRH3BCHE | |
| SCHEMBL10529057 | 0.91 | ACHE (0.51) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11178155 | 0.90 | ACHE (0.52) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11181442 | 0.90 | RECQL (0.55) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11174117 | 0.90 | ACHE (0.52) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11181879 | 0.89 | ACHE (0.51) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11178103 | 0.89 | ACHE (0.56) | ACHEHRH2HRH3 | |
| SCHEMBL11185566 | 0.88 | ACHE (0.50) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11174120 | 0.88 | ACHE (0.50) | ACHEHRH2HRH3BCHE | |
| SCHEMBL11187118 | 0.88 | HRH2 (0.52) | ACHEHRH2HRH3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837316-A | ANTIULCER AGENTS | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0214823-A2 | Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1987-03-18 | — | — | EP | disclosed |