Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11180030 | 0.99 | ACHE (0.54) | ACHEL3MBTL1MTNR1AMTNR1BHRH2 | |
| Ammonia Solution, Strong SCHEMBL11181888 | 0.98 | ACHE (0.53) | ACHEL3MBTL1MTNR1AMTNR1BHRH2 | |
| SCHEMBL11385070 | 0.92 | HRH2 (0.51) | ACHEL3MBTL1MTNR1AMTNR1BHRH2 | |
| SCHEMBL10529019 | 0.89 | ACHE (0.54) | ACHEHRH2HRH3 | |
| SCHEMBL11181224 | 0.89 | ACHE (0.54) | ACHEHRH2HRH3 | |
| SCHEMBL11178630 | 0.89 | ACHE (0.53) | ACHEHRH2HRH3 | |
| SCHEMBL11185547 | 0.88 | ACHE (0.52) | ACHEHRH2HRH3 | |
| SCHEMBL11181442 | 0.88 | RECQL (0.55) | ACHEMTNR1AMTNR1BHRH2HRH3 | |
| SCHEMBL11178155 | 0.88 | ACHE (0.52) | ACHEHRH2HRH3 | |
| SCHEMBL11186585 | 0.88 | HRH2 (0.67) | ACHEHRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024510-B1 | PHENOXYPROPYL AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1983-10-19 | — | — | EP | disclosed |
| US-4293557-A | AMIDES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| EP-0024510-A1 | Phenoxypropyl amine derivatives, process for their preparation, and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1981-03-11 | — | — | EP | disclosed |