SCHEMBL105301

SCHEMBL105301

CC(C)NCC1CCCO1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 4/20 0.44
TP53 P04637 1/20 0.44
ALOX12 P18054 1/20 0.44
ANPEP P15144 1/20 0.44
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12201638 1.00 USP2 (0.46) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL12201657 1.00 USP2 (0.46) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL9684500 0.94 KMT2A (0.42) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL8795712 0.86 USP2 (0.46) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL28463566 0.86 ANPEP (0.47) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL14018975 0.86 USP2 (0.42) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL6846193 0.86 USP2 (0.42) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL23781483 0.83 ANPEP (0.42) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL20093612 0.83 USP2 (0.40) USP2SMN1; SMN2HPGDTP53ALOX12
SCHEMBL15671001 0.83 ANPEP (0.45) USP2SMN1; SMN2HPGDTP53ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200269187-A1 ABSORBENT AND PROCESS FOR SELECTIVELY REMOVING HYDROGEN SULFIDE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2020-08-27 US claimed
EP-3678756-A1 ABSORBENT AND PROCESS FOR SELECTIVELY REMOVING HYDROGEN SULFIDE BASF SE (DE) 2020-07-15 EP claimed
CN-111093803-A Absorbent and process for selective removal of hydrogen sulfide 巴斯夫欧洲公司 2020-05-01 CN claimed
WO-2019043099-A1 ABSORBENT AND PROCESS FOR SELECTIVELY REMOVING HYDROGEN SULFIDE BASF SE (DE) 2019-03-07 WO claimed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 US disclosed
EP-4268824-A1 IMIDAZO[2,1-F][1,2,4]TRIAZINE DERIVATIVES USEFUL AS A MEDICAMENT Manros Therapeutics (FR) 2023-11-01 EP disclosed
WO-2023028534-A1 INHIBITORS OF NLRP3 PTC THERAPEUTICS, INC. (US) 2023-03-02 WO disclosed
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-09 US disclosed
WO-2023287704-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2023-01-19 WO disclosed
US-11458433-B2 Absorbent and process for selectively removing hydrogen sulfide BASF SE (DE) 2022-10-04 US disclosed
WO-2022164997-A1 METHODS FOR THE TREATMENT OF FIBROTIC DISEASE SHY THERAPEUTICS, LLC (US) 2022-08-04 WO disclosed
US-20220213091-A1 SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS GILEAD SCIENCES, INC. 2022-07-07 US disclosed
US-7238692-B2 Medical devices employing triazine compounds and compositions thereof REDDY US THERAPEUTICS, INC. (US) 2007-07-03 US disclosed
US-20070142380-A1 Viral Polymerase Inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-06-21 US disclosed
US-20070142380-A1 Viral Polymerase Inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-06-21 US disclosed
US-7223785-B2 Viral polymerase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-05-29 US disclosed
US-7223785-B2 Viral polymerase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-05-29 US disclosed
US-20070043042-A1 Such as 2-(Allyloxy)-4-(3-fluorophenyl)-6-methoxyquinoline-3-carbonitrile; for treating cardiac arrhthymias MERCK & CO., INC. (US) 2007-02-22 US disclosed
US-7169785-B2 Methods and compositions of novel triazine compounds REDDY US THERAPEUTICS, INC. (US) 2007-01-30 US disclosed
US-20040097560-A1 N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones THE PROCTER & GAMBLE COMPANY 2004-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 USP2 4219/4885SMN1; SMN2 1055/4885HPGD 1466/4885
US-20040097560-A1 N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones IL17A, CYP51A1, CD4 USP2 4227/4885SMN1; SMN2 1321/4885HPGD 317/4885
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides IRAK1, IRAK4, IRAK2 USP2 122/4885SMN1; SMN2 1811/4885HPGD 3623/4885
US-20220213091-A1 SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS CDK6, HIPK1, DCK USP2 2073/4885SMN1; SMN2 4077/4885HPGD 539/4885
US-20070043042-A1 Such as 2-(Allyloxy)-4-(3-fluorophenyl)-6-methoxyquinoline-3-carbonitrile; for treating cardiac arrhthymias KCNH2, KCNJ2, KCNQ1 USP2 3691/4885SMN1; SMN2 4502/4885HPGD 2662/4885
US-20070142380-A1 Viral Polymerase Inhibitors POLM, POLR2H, POLR2A USP2 3356/4885SMN1; SMN2 1649/4885HPGD 4832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.