Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10430089 | 0.91 | KDM4E (0.70) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9443488 | 0.86 | KDM4E (0.79) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL48002 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10861606 | 0.79 | LMNA (0.82) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10760272 | 0.79 | LMNA (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10658530 | 0.79 | LMNA (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL30528254 | 0.77 | LMNA (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29007962 | 0.76 | LMNA (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29007959 | 0.76 | LMNA (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29085944 | 0.76 | LMNA (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131839-B1 | QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-02-01 | — | — | EP | disclosed |