Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 6/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.43 |
| ▸ | MERTK | Q12866 | 6/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 6/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503228 | 1.00 | DNM2 (0.44) | DNM2KMT2AFLT3TYRO3MERTK | |
| SCHEMBL10502792 | 1.00 | DNM2 (0.44) | DNM2KMT2AFLT3TYRO3MERTK | |
| SCHEMBL10502394 | 1.00 | DNM2 (0.44) | DNM2KMT2AFLT3TYRO3MERTK | |
| SCHEMBL10504062 | 1.00 | DNM2 (0.44) | DNM2KMT2AFLT3TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL10503395 | 0.98 | DNM2 (0.43) | DNM2KMT2AFLT3TYRO3MERTK | |
| SCHEMBL10503435 | 0.80 | HPGD (0.49) | — | |
| SCHEMBL10503163 | 0.80 | HPGD (0.49) | — | |
| SCHEMBL10503381 | 0.78 | SCN9A (0.44) | — | |
| SCHEMBL10502715 | 0.78 | SCN9A (0.44) | — | |
| SCHEMBL10369771 | 0.78 | KMT2A (0.54) | DNM2KMT2AKCNH3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989000423-A1 | 2-AMINO-5-HYDROXY-4-PYRIMIDONES | PFIZER INC. (US) | 1989-01-26 | — | — | WO | disclosed |