Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15610865 | 0.79 | KMT2A (0.55) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 | |
| SCHEMBL990297 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2AL3MBTL1GAAPOLB | |
| SCHEMBL2510372 | 0.78 | KMT2A (0.56) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 | |
| SCHEMBL6957487 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2AL3MBTL1GAAMEN1 | |
| SCHEMBL10531978 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 | |
| SCHEMBL5603398 | 0.77 | KMT2A (0.60) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 | |
| SCHEMBL15610829 | 0.77 | KMT2A (0.54) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 | |
| SCHEMBL29270165 | 0.77 | OPRM1 (0.60) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 | |
| SCHEMBL5067751 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KMT2AL3MBTL1GAAPOLB | |
| SCHEMBL12682257 | 0.76 | SMN1; SMN2 (0.61) | ALDH1A1KMT2AL3MBTL1GAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1168657-A | — | — | None | — | — | JP | disclosed |
| JP-H01168657-A | BENZAMIDE DERIVATIVE | TEIKOKU CHEM IND CORP LTD | 1989-07-04 | — | — | JP | disclosed |