Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483390 | 0.81 | PSEN1 (0.53) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7431999 | 0.76 | REN (0.39) | RENPSMB5 | |
| SCHEMBL7432795 | 0.75 | CTSD (0.38) | REN | |
| SCHEMBL7431811 | 0.74 | PSMB5 (0.41) | RENPSMB5PSEN1PSEN2APH1B | |
| SCHEMBL9574983 | 0.71 | REN (0.46) | REN | |
| SCHEMBL7433079 | 0.71 | REN (0.62) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7432802 | 0.70 | REN (0.53) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13363680 | 0.68 | NPY4R (0.59) | RENPSMB5 | |
| SCHEMBL17741125 | 0.68 | PSMB5 (0.60) | RENPSMB5 | |
| SCHEMBL7432319 | 0.67 | PSMB5 (0.40) | RENPSMB5PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989007940-A1 | 1,2-HYDROXY PHOSPHONATES AND DERIVATIVES THEREOF | E.R. SQUIBB & SONS, INC. (US) | 1989-09-08 | — | — | WO | disclosed |