Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flutiazin SCHEMBL193601 | 0.81 | NOX1 (0.58) | HSD17B10ALDH1A1HPGDKDM4EUSP2 | |
| Flutiazin SCHEMBL29394002 | 0.81 | NOX1 (0.58) | HSD17B10ALDH1A1HPGDKDM4EUSP2 | |
| Flutiazin SCHEMBL11811863 | 0.80 | NOX1 (0.57) | HSD17B10ALDH1A1HPGDKDM4EUSP2 | |
| Flutiazin SCHEMBL11818117 | 0.76 | NOX1 (0.51) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL3997039 | 0.75 | CFD (0.74) | CFDHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL11823962 | 0.74 | NOX1 (0.49) | HSD17B10ALDH1A1HPGDKDM4EUSP2 | |
| SCHEMBL11808295 | 0.74 | NOX1 (0.44) | ALDH1A1KDM4EMAPTALOX15CYBB | |
| Flufenisal SCHEMBL11333508 | 0.74 | CFD (0.81) | CFDHSD17B10ALDH1A1HPGDKDM4E | |
| Flufenisal SCHEMBL38781 | 0.74 | CFD (0.81) | CFDHSD17B10ALDH1A1HPGDKDM4E | |
| Flufenisal SCHEMBL3693207 | 0.72 | CFD (0.79) | CFDHSD17B10ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989008119-A1 | HIGH MOLECULAR WEIGHT PRODRUG DERIVATIVES OF ANTI-INFLAMMATORY DRUGS | SELCH LARSEN CLAUS (DK) | 1989-09-08 | — | — | WO | disclosed |