Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.40 |
| ▸ | CALCR | P30988 | 5/20 | 0.40 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377176 | 0.94 | EPHA2 (0.49) | EPHA2KDM1ACXCR4OPRM1OPRK1 | |
| SCHEMBL8969918 | 0.91 | EPHA2 (0.49) | EPHA2KDM1ACXCR4OPRM1XIAP | |
| SCHEMBL8970642 | 0.89 | EPHA2 (0.47) | EPHA2KDM1AXIAPCALCRLMAOB | |
| SCHEMBL9691462 | 0.88 | EPHA2 (0.59) | EPHA2KDM1AOPRM1OPRK1CALCRL | |
| SCHEMBL9807265 | 0.87 | EPHA2 (0.61) | EPHA2KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL7780983 | 0.87 | EPHA2 (0.41) | EPHA2CXCR4OPRM1OPRK1 | |
| SCHEMBL10435105 | 0.86 | EPHA2 (0.51) | EPHA2KDM1ACXCR4OPRM1OPRK1 | |
| SCHEMBL10378224 | 0.85 | EPHA2 (0.48) | EPHA2KDM1AXIAPCALCRLMAOB | |
| SCHEMBL10378950 | 0.85 | EPHA2 (0.48) | EPHA2KDM1ACXCR4OPRM1OPRK1 | |
| SCHEMBL30118981 | 0.84 | EPHA2 (0.47) | EPHA2CALCRLGRB2RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011289-A1 | PEPTIDES HAVING T CELL HELPER ACTIVITY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1989-11-30 | — | — | WO | disclosed |