Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.54 |
| ▸ | NTSR2 | O95665 | 7/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 7/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691462 | 0.95 | EPHA2 (0.59) | EPHA2AGTR2AGTR1KDM1ASLC6A2 | |
| SCHEMBL9807269 | 0.93 | EPHA2 (0.63) | EPHA2AGTR2AGTR1KDM1ANTSR2 | |
| SCHEMBL9807245 | 0.93 | EPHA2 (0.61) | EPHA2AGTR2AGTR1NTSR2NTSR1 | |
| SCHEMBL9807252 | 0.89 | EPHA2 (0.62) | EPHA2KDM1ANMUR2NMUR1MAOB | |
| SCHEMBL9807306 | 0.89 | EPHA2 (0.62) | EPHA2KDM1ANMUR2NMUR1MAOB | |
| SCHEMBL9807256 | 0.89 | EPHA2 (0.59) | EPHA2KDM1ANTSR2NTSR1SORT1 | |
| SCHEMBL9691456 | 0.88 | EPHA2 (0.61) | EPHA2AGTR2AGTR1KDM1A | |
| SCHEMBL9551316 | 0.88 | EPHA2 (0.59) | EPHA2AGTR2AGTR1NTSR2NTSR1 | |
| SCHEMBL9807257 | 0.87 | NTSR1 (0.62) | EPHA2AGTR2AGTR1NTSR2NTSR1 | |
| SCHEMBL10533153 | 0.87 | EPHA2 (0.49) | EPHA2KDM1ANTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146266-B1 | ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0146266-A2 | Enzyme-resistant immunomodulatory peptides | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |