SCHEMBL10533746

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	15/20	0.45

▸	CTSD	P07339	1/20	0.44

▸	BACE2	Q9Y5Z0	2/20	0.43

▸	GLP1R	P43220	2/20	0.42

▸	SCTR	P47872	1/20	0.42

▸	GRPR	P30550	1/20	0.41

▸	RAMP3	O60896	1/20	0.41

▸	CALCR	P30988	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31256975	0.88	BACE1 (0.42)	BACE1CTSDBACE2GLP1RSCTR
SCHEMBL29757432	0.86	BACE1 (0.48)	BACE1CTSDBACE2
SCHEMBL31410884	0.85	BACE1 (0.48)	BACE1CTSDBACE2GLP1RSCTR
SCHEMBL21148859	0.85	ERAP2 (0.40)	BACE1BACE2
SCHEMBL29624554	0.85	BACE1 (0.43)	BACE1GLP1R
SCHEMBL30720017	0.85	BACE1 (0.46)	BACE1CTSDBACE2GLP1RSCTR
SCHEMBL31514364	0.85	BACE1 (0.47)	BACE1GLP1RCALCR
SCHEMBL31410826	0.85	GLP1R (0.47)	BACE1BACE2GLP1RSCTR
SCHEMBL30262179	0.84	GLP1R (0.51)	GLP1RSCTR
SCHEMBL30512656	0.84	BACE1 (0.45)	BACE1CTSDBACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1989010416-A1	PROTECTIVE PEPTIDES DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUS-1 gp160	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US)	1989-11-02	—	—	WO	disclosed