SCHEMBL29624554

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)N)[C@@H](C)CC)[C@@H](C)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	2/20	0.43

▸	MAGI3	Q5TCQ9	1/20	0.42

▸	ENPEP	Q07075	5/20	0.40

▸	GLP1R	P43220	2/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29771459	0.94	BACE1 (0.41)	BACE1MAGI3ENPEPGLP1R
SCHEMBL31663833	0.89	BACE1 (0.49)	BACE1MAGI3GLP1R
SCHEMBL30919405	0.89	BACE1 (0.41)	BACE1MAGI3ENPEPGLP1R
SCHEMBL29691686	0.85	CTSD (0.38)	ENPEP
SCHEMBL10533746	0.85	BACE1 (0.45)	BACE1GLP1R
SCHEMBL31257072	0.85	MAGI3 (0.48)	BACE1MAGI3GLP1R
SCHEMBL7555807	0.85	ENPEP (0.42)	BACE1MAGI3ENPEPGLP1R
SCHEMBL29625183	0.83	ENPEP (0.39)	ENPEP
SCHEMBL21766696	0.83	BACE1 (0.43)	BACE1
SCHEMBL21766761	0.82	BACE1 (0.41)	BACE1MAGI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11344606-B2	Parathyroid hormone fusion polypeptide	UNIVERSITY OF SHEFFIELD (GB)	2022-05-31	—	—	US	disclosed