SCHEMBL31256975

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.44

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	12/20	0.42

▸	OPRM1	P35372	2/20	0.42

▸	OPRD1	P41143	2/20	0.42

▸	GRPR	P30550	2/20	0.42

▸	BACE2	Q9Y5Z0	3/20	0.41

▸	CTSD	P07339	1/20	0.41

▸	GLP1R	P43220	2/20	0.40

▸	SCTR	P47872	1/20	0.40

▸	KISS1R	Q969F8	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31514368	0.89	BACE1 (0.49)	BACE1GRPRBACE2CTSD
SCHEMBL30939707	0.88	MC4R (0.40)	OPRM1OPRD1GLP1RSCTR
SCHEMBL31257073	0.88	MAGI3 (0.44)	BACE1GRPRBACE2CTSDGLP1R
SCHEMBL10533746	0.88	BACE1 (0.45)	BACE1GRPRBACE2CTSDGLP1R
SCHEMBL31257065	0.87	MAGI3 (0.42)	BACE1GRPRBACE2CTSDGLP1R
SCHEMBL31257072	0.86	MAGI3 (0.48)	BACE1GLP1R
SCHEMBL29680113	0.86	BACE1 (0.48)	BACE1BACE2CTSD
SCHEMBL31453800	0.85	OPRM1 (0.40)	BACE1OPRM1OPRD1
SCHEMBL31663833	0.85	BACE1 (0.49)	BACE1CTSDGLP1R
SCHEMBL29757432	0.85	BACE1 (0.48)	BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed