Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535333 | 0.97 | THRB (0.39) | THRBTSHRNAAA | |
| SCHEMBL10536764 | 0.93 | TSHR (0.42) | THRBTSHRNAAAALDH1A1 | |
| SCHEMBL10534897 | 0.92 | TSHR (0.44) | THRBTSHRNAAA | |
| SCHEMBL10536771 | 0.92 | TSHR (0.47) | THRBTSHRNAAA | |
| SCHEMBL10533618 | 0.90 | TSHR (0.39) | THRBTSHRNAAA | |
| SCHEMBL10532982 | 0.89 | TSHR (0.41) | THRBTSHRNAAA | |
| SCHEMBL10535835 | 0.88 | TSHR (0.47) | THRBTSHRNAAAALDH1A1 | |
| SCHEMBL10536852 | 0.87 | TSHR (0.49) | THRBTSHRNAAAALDH1A1 | |
| SCHEMBL10533494 | 0.87 | TSHR (0.49) | THRBTSHRNAAAALDH1A1 | |
| SCHEMBL10533497 | 0.86 | TSHR (0.49) | THRBTSHRNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011496-A1 | SIDE-CHAIN POLYMERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-30 | — | — | WO | disclosed |