Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083629 | 0.81 | IKBKB (0.50) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL21411372 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL6310194 | 0.78 | LMNA (0.50) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL10746533 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL11466890 | 0.75 | HPGD (0.50) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL3870328 | 0.74 | SMN1; SMN2 (0.66) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL3932937 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL8241193 | 0.73 | MAPK13 (0.45) | ALDH1A1LMNAMAPK1NPSR1MAPT | |
| SCHEMBL14231868 | 0.73 | NPSR1 (0.46) | ALDH1A1LMNAMAPK1TSHRNPSR1 | |
| SCHEMBL7894867 | 0.73 | MAPT (0.71) | ALDH1A1LMNAMAPK1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182165-B1 | THIENYL CONDENSED-PYRAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1989-08-16 | — | — | EP | disclosed |