Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532237 | 0.79 | ADCY5 (0.46) | ADCY5ADORA2APDE3ATRPM2FGFR1 | |
| Hydrochloric Acid SCHEMBL9561683 | 0.78 | ADCY5 (0.45) | ADCY5ADORA2APDE3ATRPM2FGFR1 | |
| SCHEMBL10362340 | 0.71 | ADORA2A (0.61) | ADCY5ADORA2ACYP1A2TSHRADORA1 | |
| SCHEMBL20974519 | 0.70 | ADCY5 (0.56) | ADCY5ADORA2APDE3ATRPM2FGFR1 | |
| SCHEMBL10896726 | 0.70 | ADCY5 (0.40) | ADCY5ADORA2ATRPM2FGFR1CYP1A2 | |
| SCHEMBL10902555 | 0.70 | ADCY5 (0.40) | ADCY5ADORA2ATRPM2FGFR1CYP1A2 | |
| SCHEMBL7812370 | 0.69 | ADORA2A (0.63) | ADCY5ADORA2ACYP1A2TSHRADORA1 | |
| SCHEMBL10889183 | 0.68 | ADORA2A (0.39) | ADCY5ADORA2ACYP1A2ADORA1 | |
| SCHEMBL6060865 | 0.66 | ADORA2A (0.48) | ADCY5ADORA2APDE3ACYP1A2TSHR | |
| SCHEMBL20975063 | 0.66 | ADCY5 (0.50) | ADCY5ADORA2APDE3ATRPM2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | claimed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | claimed |