Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902555 | 1.00 | ADCY5 (0.40) | ADCY5TAAR1ADORA2AALDH1A1CYP3A4 | |
| SCHEMBL10532237 | 0.78 | ADCY5 (0.46) | ADCY5ADORA2ACYP2D6FGFR1TRPM2 | |
| Hydrochloric Acid SCHEMBL9561683 | 0.77 | ADCY5 (0.45) | ADCY5ADORA2ACYP2D6FGFR1TRPM2 | |
| SCHEMBL9561494 | 0.77 | ADCY5 (0.40) | ADCY5TAAR1ADORA2A | |
| SCHEMBL9560980 | 0.75 | MARS1 (0.37) | ADCY5 | |
| SCHEMBL10920956 | 0.75 | ADCY5 (0.38) | ADCY5ALDH1A1FGFR1P2RY1 | |
| SCHEMBL8466911 | 0.74 | ADCY5 (0.37) | ADCY5ADORA2AALDH1A1TRPM2P2RY1 | |
| SCHEMBL8464634 | 0.72 | CYP1A2 (0.49) | ADCY5CYP2D6CYP1A2 | |
| SCHEMBL10889183 | 0.72 | ADORA2A (0.39) | ADCY5ADORA2ACYP1A2 | |
| SCHEMBL9561486 | 0.71 | PRMT5 (0.39) | ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077460-B1 | PURINE COMPOUNDS ENDOWED WITH IMMUNOMODULATING ACTIVITY | CO PHARMA CORPORATION S.r.l. (IT) | 1986-10-15 | — | — | EP | disclosed |
| US-4567182-A | PURINE DERIVATIVES | CO PHARMA CORPORATION S.R.L. (IT) | 1986-01-28 | — | — | US | disclosed |