Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762834 | 0.76 | LMNA (0.46) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL6692258 | 0.74 | ADAMTS5 (0.35) | HDAC1KDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL10574702 | 0.72 | ADAMTS5 (0.42) | ALDH1A1ADAMTS4ADAM17ADAMTS5 | |
| SCHEMBL10576904 | 0.72 | ADAMTS5 (0.42) | ALDH1A1ADAMTS4ADAM17ADAMTS5 | |
| SCHEMBL2138946 | 0.72 | ADAMTS5 (0.42) | ALDH1A1ADAMTS4ADAM17ADAMTS5 | |
| SCHEMBL7756418 | 0.72 | LMNA (0.38) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 | |
| SCHEMBL15692524 | 0.71 | LMNA (0.31) | ALDH1A1LMNA | |
| SCHEMBL6691745 | 0.71 | ADAMTS5 (0.37) | HDAC1KDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL4618645 | 0.71 | KDM4E (0.32) | HDAC1KDM4EALDH1A1CYP3A4GABRB3 | |
| SCHEMBL6693034 | 0.69 | LMNA (0.40) | KDM4EALDH1A1CYP3A4GABRB3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871552-A | 5-ALKYLIDENE OR 5-HYDROXY-5-ALKYL DERIVATIVES | W. R. GRACE & CO.-CONN. (US) | 1989-10-03 | — | — | US | claimed |
| US-4744990-A | NUTRIENTS FOR ANIMALS | W. R. GRACE & CO. (US) | 1988-05-17 | — | — | US | claimed |
| EP-0261982-A1 | Animal food supplements | W.R. GRACE & CO. (US) | 1988-03-30 | — | — | EP | claimed |
| CN-117776947-A | Preparation method of sodium and calcium raceme isoleucine | 河北天成药业股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117603042-A | Preparation method and application of ketoleucine salt derivative | 河北天成药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-4871552-A | 5-ALKYLIDENE OR 5-HYDROXY-5-ALKYL DERIVATIVES | W. R. GRACE & CO.-CONN. (US) | 1989-10-03 | — | — | US | disclosed |