Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324724 | 0.80 | TDO2 (0.61) | KDM4ELMNAHTR2AHTR2CHTR2B | |
| SCHEMBL18324726 | 0.80 | CHEK1 (0.49) | KDM4ELMNAHTR2AHTR2CHTR2B | |
| SCHEMBL25243471 | 0.79 | CHEK1 (0.43) | KDM4ELMNAPOLBHTR1AALOX15 | |
| SCHEMBL25253543 | 0.77 | HTR2A (0.68) | KDM4EHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL26911745 | 0.76 | LRRK2 (0.58) | KDM4ELMNAHTR2AHTR2CHTR2B | |
| SCHEMBL24377908 | 0.75 | SLC6A4 (0.42) | KDM4ELMNAPOLBHTR1AALOX15 | |
| SCHEMBL24331226 | 0.75 | GRM1 (0.55) | HTR6 | |
| SCHEMBL18561354 | 0.75 | FGFR1 (0.44) | KDM4EPOLBALOX15SLC6A4HSD17B10 | |
| SCHEMBL1513098 | 0.74 | HTR2A (0.63) | KDM4EHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL25243459 | 0.73 | SLC6A4 (0.38) | KDM4ELMNAPOLBHTR1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989010924-A1 | INDAZOLE DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-11-16 | — | — | WO | disclosed |