Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24377932 | 0.78 | SLC6A4 (0.62) | SLC6A4HTR6KDM4ELMNAPOLB | |
| SCHEMBL29546618 | 0.78 | SLC6A4 (0.62) | SLC6A4HTR6KDM4ELMNAPOLB | |
| SCHEMBL10535366 | 0.75 | KDM4E (0.57) | SLC6A4HTR6HTR2AKDM4ELMNA | |
| SCHEMBL25243471 | 0.73 | CHEK1 (0.43) | SLC6A4HTR6KDM4ELMNAPOLB | |
| SCHEMBL29562759 | 0.72 | AXL (0.64) | — | |
| SCHEMBL31543504 | 0.69 | MAPK1 (0.48) | — | |
| SCHEMBL21037217 | 0.68 | QDPR (0.42) | SLC6A4HTR6 | |
| SCHEMBL21037746 | 0.67 | CHRNB2 (0.60) | — | |
| SCHEMBL16580770 | 0.65 | ADORA2A (0.44) | HSD17B10 | |
| SCHEMBL29562995 | 0.65 | ADORA2A (0.44) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083560-A1 | TYK2 SELECTIVE INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 | 2022-04-28 | — | — | WO | disclosed |