SCHEMBL10535546

SCHEMBL10535546

C[C@H](N)C(=O)C1(C(=O)[C@H](C)N)CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TSHR P16473 2/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
BLM P54132 1/20 0.30
CACNA2D1 P54289 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535530 1.00 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2TSHRUSP2LMNA
SCHEMBL4952590 0.74 SLC7A5 (0.38)
SCHEMBL6348633 0.73
SCHEMBL15630616 0.72 TSHR (0.31) ALDH1A1TSHRCYP2C19
SCHEMBL4948965 0.71 SLC7A5 (0.39)
SCHEMBL6345440 0.70 NPSR1 (0.31)
SCHEMBL23904782 0.68
Alanine SCHEMBL28226154 0.68 SLC7A5 (0.50) ALDH1A1
Cyclohexane SCHEMBL16432389 0.68 SLC7A5 (0.50) ALDH1A1
Cyclohexane SCHEMBL16432387 0.68 SLC7A5 (0.50) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4804699-A Monomeric and oligomeric glutarate-based light stabilizers for plastics ICI AMERICAS INC. (US) 1989-02-14 US claimed
EP-0291238-A2 Monomeric and oligomeric glutarate-based light stabilisers for plastics ICI AMERICAS INC. (US) 1988-11-17 EP claimed
US-4689360-A SPIRO RING CONTAINING ESTERS ICI AMERICAS INC. (US) 1987-08-25 US claimed
EP-0219333-A2 Oligomeric malonates, useful as light stabilizers for plastics ICI AMERICAS INC. (US) 1987-04-22 EP claimed