Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 8/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.31 |
| ▸ | FAP | Q12884 | 4/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.31 |
| ▸ | PREP | P48147 | 2/20 | 0.31 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952590 | 0.98 | SLC7A5 (0.38) | SLC7A5DPP4DPP7FAPDPP8 | |
| SCHEMBL4953896 | 0.81 | DPP4 (0.41) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL4955670 | 0.80 | DPP4 (0.40) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL10535530 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL10535546 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL24798590 | 0.64 | SLC7A5 (0.41) | SLC7A5DPP4DPP7FAPDPP8 | |
| SCHEMBL19663543 | 0.64 | SLC7A5 (0.41) | SLC7A5DPP4DPP7FAPDPP8 | |
| SCHEMBL21367436 | 0.64 | SLC7A5 (0.41) | SLC7A5DPP4DPP7FAPDPP8 | |
| SCHEMBL2632698 | 0.64 | SLC7A5 (0.41) | SLC7A5DPP4DPP7FAPDPP8 | |
| Valine SCHEMBL9318955 | 0.62 | SLC7A5 (0.83) | SLC7A5DPP4DPP7FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368576-B2 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents | PROBIODRUG AG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-7368421-B2 | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis | PROBIODRUG AG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-20070207946-A1 | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels | POSPISILIK ANDREW J | 2007-09-06 | — | — | US | disclosed |
| US-20060293248-A1 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents | PROBIODRUG AG | 2006-12-28 | — | — | US | disclosed |
| US-7109347-B2 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents | PROBIODRUG AG (DE) | 2006-09-19 | — | — | US | disclosed |
| CN-1688599-A | Novel use of dipeptidyl peptidase IV inhibitor | PROBIODRUG AG (DE) | 2005-10-26 | — | — | CN | disclosed |
| US-20050171025-A1 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents | PROBIODRUG AG (DE) | 2005-08-04 | — | — | US | disclosed |
| US-20050107308-A1 | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels | PROSIDION LIMITED (GB) | 2005-05-19 | — | — | US | disclosed |
| CN-1464881-A | New dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents | PROBIODRUG AG (CN) | 2003-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107308-A1 | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels | DPP4, DPP3, DPP9 | SLC7A5 354/4885DPP4 1/4885DPP7 5/4885 |
| US-20060293248-A1 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents | DPP4, DPP3, DNPEP | SLC7A5 852/4885DPP4 1/4885DPP7 4/4885 |
| US-20070207946-A1 | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels | DPP4, DPP3, DPP9 | SLC7A5 354/4885DPP4 1/4885DPP7 5/4885 |
| US-20050171025-A1 | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents | DPP4, DPP3, DNPEP | SLC7A5 852/4885DPP4 1/4885DPP7 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.