Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750980 | 0.92 | KDM4E (0.79) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9550186 | 0.90 | ALDH1A1 (0.88) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL712564 | 0.85 | KDM4E (0.58) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL712563 | 0.85 | KDM4E (0.58) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| Famciclovir SCHEMBL29357294 | 0.85 | KDM4E (1.00) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| Famciclovir SCHEMBL2949 | 0.85 | KDM4E (1.00) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| Famciclovir SCHEMBL8190642 | 0.85 | KDM4E (1.00) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| Famciclovir SCHEMBL3932051 | 0.84 | KDM4E (0.98) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| Famciclovir SCHEMBL6471652 | 0.84 | KDM4E (0.98) | RXFP1KDM4EALDH1A1HPGDADRA1A | |
| Famciclovir SCHEMBL29098544 | 0.84 | KDM4E (0.98) | RXFP1KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989010923-A1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | MEDIVIR AB (SE) | 1989-11-16 | — | — | WO | disclosed |