Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TLR4 | O00206 | 4/20 | 0.43 |
| ▸ | TLR2 | O60603 | 4/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535968 | 1.00 | FBP1 (0.50) | FBP1HPRT1ALDH1A1NPSR1LMNA | |
| SCHEMBL496 | 0.81 | FBP1 (0.54) | FBP1HPRT1ALDH1A1NPSR1LMNA | |
| SCHEMBL497 | 0.81 | FBP1 (0.54) | FBP1HPRT1ALDH1A1NPSR1LMNA | |
| SCHEMBL27673733 | 0.80 | FBP1 (0.55) | FBP1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL4851358 | 0.75 | PSMB5 (0.46) | HPRT1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL16520429 | 0.74 | FBP1 (0.52) | FBP1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL29273221 | 0.74 | FBP1 (0.53) | FBP1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL458434 | 0.74 | FBP1 (0.53) | FBP1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL458238 | 0.74 | FBP1 (0.53) | FBP1ALDH1A1NPSR1LMNAMAPT | |
| SCHEMBL14089427 | 0.74 | LMNA (0.40) | ALDH1A1NPSR1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |