Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218 | 0.81 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL5547472 | 0.76 | AGTR1 (0.72) | AGTR1 | |
| SCHEMBL478 | 0.72 | AGTR1 (0.69) | AGTR1 | |
| SCHEMBL29308431 | 0.70 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL5154732 | 0.70 | KMO (0.67) | — | |
| SCHEMBL8434246 | 0.69 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL9031390 | 0.69 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL8096101 | 0.67 | PPARG (0.54) | PPARGAGTR1 | |
| SCHEMBL7890351 | 0.67 | AGTR1 (0.60) | AGTR1 | |
| SCHEMBL3373963 | 0.66 | POLB (0.63) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |