Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014 | 0.91 | GP6 (0.66) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL17949543 | 0.82 | PPARG (0.57) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL21083688 | 0.82 | GP6 (0.59) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL21083964 | 0.81 | GP6 (0.56) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL3459616 | 0.81 | PPARG (0.59) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL21083785 | 0.79 | GP6 (0.55) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL21083673 | 0.79 | GP6 (0.55) | GP6AGTR1AGTR2 | |
| SCHEMBL13278168 | 0.79 | PPARG (0.53) | GP6AGTR1AGTR2PPARG | |
| SCHEMBL12716740 | 0.78 | PPARG (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL6430 | 0.78 | PPARG (0.61) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |