Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536726 | 1.00 | ALDH1A1 (0.61) | ALDH1A1GAAHCAR2TAAR1CA14 | |
| SCHEMBL10539767 | 1.00 | ALDH1A1 (0.61) | ALDH1A1GAAHCAR2TAAR1CA14 | |
| SCHEMBL28176602 | 0.82 | CA14 (0.42) | ALDH1A1GAACA14SMN1; SMN2TSHR | |
| SCHEMBL4572573 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAHCAR2TAAR1SMN1; SMN2 | |
| SCHEMBL4572574 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAHCAR2TAAR1SMN1; SMN2 | |
| SCHEMBL11222703 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAHCAR2TAAR1SMN1; SMN2 | |
| SCHEMBL10935338 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAHCAR2TAAR1SMN1; SMN2 | |
| SCHEMBL9435294 | 0.77 | MAPT (0.48) | ALDH1A1GAATAAR1SMN1; SMN2MEN1 | |
| SCHEMBL10823780 | 0.76 | GAA (1.00) | ALDH1A1GAAHCAR2TAAR1SMN1; SMN2 | |
| SCHEMBL14355649 | 0.76 | GAA (1.00) | ALDH1A1GAAHCAR2TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H645-H | Process for the conversion of maleic acid derivatives to their corresponding fumaric isomers | THE NUTRASWEET COMPANY (US) | 1989-06-06 | — | — | US | disclosed |