Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620390 | 0.87 | RAB9A (0.49) | MAPTAKT1MAPK1NPC1RAB9A | |
| SCHEMBL10621126 | 0.86 | SMN1; SMN2 (0.49) | MAPTAKT1MAPK1NPC1RAB9A | |
| SCHEMBL10621121 | 0.86 | SMN1; SMN2 (0.49) | MAPTAKT1MAPK1NPC1RAB9A | |
| SCHEMBL27620181 | 0.79 | PPARG (0.54) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL1686722 | 0.77 | GAA (0.58) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL9943346 | 0.77 | GAA (0.58) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL11069381 | 0.77 | SMN1; SMN2 (0.48) | MAPTAKT1NPC1RAB9AGAA | |
| SCHEMBL11069383 | 0.77 | SMN1; SMN2 (0.48) | MAPTAKT1NPC1RAB9AGAA | |
| SCHEMBL10536726 | 0.77 | ALDH1A1 (0.61) | MAPTL3MBTL1MAPK1GAAKMT2A | |
| SCHEMBL10539767 | 0.77 | ALDH1A1 (0.61) | MAPTL3MBTL1MAPK1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994014768-A1 | NOVEL PYRROLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1994-07-07 | — | — | WO | disclosed |