Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838778 | 1.00 | GAA (0.35) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL9686969 | 0.86 | GAA (0.39) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL9686966 | 0.86 | GAA (0.39) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL12417451 | 0.83 | GAA (0.37) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL3875356 | 0.81 | GAA (0.36) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL1343209 | 0.81 | GAA (0.36) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL1343210 | 0.81 | GAA (0.36) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL10541861 | 0.80 | ALDH1A1 (0.38) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL9510054 | 0.80 | KMT2A (0.35) | GAANPSR1MAPTKMT2ALMNA | |
| SCHEMBL9510747 | 0.80 | ALDH1A1 (0.38) | GAANPSR1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816451-A | Antibacterial 1,8-bridged 4-quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |