Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511932 | 0.85 | MEN1 (0.36) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL5534138 | 0.85 | MEN1 (0.36) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL10392582 | 0.85 | MEN1 (0.37) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL26365723 | 0.82 | MEN1 (0.35) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL9510747 | 0.82 | ALDH1A1 (0.38) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL10541861 | 0.82 | ALDH1A1 (0.38) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL29281063 | 0.81 | CYP2D6 (0.43) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL10537823 | 0.80 | GAA (0.35) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL9838778 | 0.80 | GAA (0.35) | KMT2AMEN1NPSR1MAPTLMNA | |
| SCHEMBL12916941 | 0.80 | MAPT (0.35) | KMT2AMEN1NPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563733-A1 | Use of 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxacin-6-carboxylic acid- and esters for the manufacture of a medicament for the treatment of viral diseases | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |