Acrylamide

Acrylamide

SCHEMBL10537862

C=CC(=O)N(CCC)CCC.C=CC(N)=O.C=CC(N)=O.C=CC(N)=O.C=CC(N)=O.C=CC(N)=O.C=CC(N)=O.C=CC(N)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
ALDH1A1 P00352 3/20 0.46
FGFR4 P22455 1/20 0.46
ZDHHC20 Q5W0Z9 2/20 0.45
ZDHHC2 Q9UIJ5 1/20 0.45
MAPK1 P28482 1/20 0.42
CA12 O43570 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
APP P05067 2/20 0.36
HPGD P15428 2/20 0.35
TP53 P04637 1/20 0.34
CA1 P00915 2/20 0.33
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36287 0.91 ZDHHC20 (0.50) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL23421740 0.89 ZDHHC20 (0.49) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
Hydrogen Sulfide SCHEMBL27807905 0.89 ZDHHC20 (0.49) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL27555253 0.86 ZDHHC20 (0.44) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL19610469 0.85 ZDHHC20 (0.59) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
Ethylene Glycol SCHEMBL28659119 0.85 ZDHHC20 (0.46) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL23421037 0.85 ZDHHC20 (0.54) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL8377943 0.84 ZDHHC20 (0.42) TSHRALDH1A1FGFR4ZDHHC20ZDHHC2
SCHEMBL23421122 0.83 ZDHHC20 (0.62) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL4577787 0.83 ZDHHC20 (0.57) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4831095-A A DIALKYLAMINOALKYLACRYLAMIDE COMONOMER; DYEABILITY; CATIONIC POLYMERS; ANTISTATIC AGENTS; ELECTROCONDUCTIVITY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-16 US disclosed