SCHEMBL19610469

SCHEMBL19610469

C=CC(=O)N(CCC)CCCCN(CCC)C(=O)C=C

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 4/20 0.59
ZDHHC2 Q9UIJ5 2/20 0.59
TSHR P16473 3/20 0.43
MAPK1 P28482 1/20 0.43
CA12 O43570 5/20 0.41
CA9 Q16790 5/20 0.41
CA2 P00918 3/20 0.41
CA1 P00915 4/20 0.39
HPGD P15428 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
APP P05067 2/20 0.36
TP53 P04637 1/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23421122 0.98 ZDHHC20 (0.62) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL15233352 0.96 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL23421037 0.96 ZDHHC20 (0.54) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL15233351 0.94 ZDHHC20 (0.68) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL12200652 0.94 ZDHHC20 (0.68) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL6510490 0.94 ZDHHC20 (0.68) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL4577787 0.94 ZDHHC20 (0.57) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL36287 0.93 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRMAPK1CA12
SCHEMBL23421169 0.91 ZDHHC20 (0.64) ZDHHC20ZDHHC2TSHRCA12CA9
SCHEMBL1503291 0.91 ZDHHC20 (0.69) ZDHHC20ZDHHC2TSHRCA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230135413-A1 CURABLE WATER-BASED COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE WATER-BASED COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE WATER-BASED INK, STORED CONTAINER, TWO-DIMENSIONAL OR THREE-DIMENSIONAL IMAGE FORMING APPARATUS, TWO-DIMENSIONAL OR THREE-DIMENSIONAL IMAGE FORMING METHOD, CURED PRODUCT, AND DECORATED BODY RICOH COMPANY, LTD. (JP) 2023-05-04 US disclosed
US-20230135413-A1 CURABLE WATER-BASED COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE WATER-BASED COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE WATER-BASED INK, STORED CONTAINER, TWO-DIMENSIONAL OR THREE-DIMENSIONAL IMAGE FORMING APPARATUS, TWO-DIMENSIONAL OR THREE-DIMENSIONAL IMAGE FORMING METHOD, CURED PRODUCT, AND DECORATED BODY RICOH COMPANY, LTD. (JP) 2023-05-04 US disclosed
EP-3246001-B1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2023-03-29 EP disclosed
US-20210155814-A1 ACTIVE-ENERGY-RAY-CURABLE AQUEOUS COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE AQUEOUS INK, STORED CONTAINER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, CURED PRODUCT, AND DECORATED PRODUCT RICOH COMPANY, LTD. (JP) 2021-05-27 US disclosed
US-11000454-B2 Dental composition DENTSPLY SIRONA INC. (US) 2021-05-11 US disclosed
US-11000454-B2 Dental composition DENTSPLY SIRONA INC. (US) 2021-05-11 US disclosed
US-20190117523-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-04-25 US disclosed
US-20190117523-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-04-25 US disclosed
WO-2017198840-A1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2017-11-23 WO disclosed
WO-2017198840-A1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2017-11-23 WO disclosed
EP-3246001-A1 DENTAL COMPOSITION DENTSPLY DETREY GmbH (DE) 2017-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11000454-B2 Dental composition PPIP5K2, INPP5D, DCPS ZDHHC20 1646/4885ZDHHC2 2407/4885TSHR 4113/4885
US-20190117523-A1 DENTAL COMPOSITION PPIP5K2, INPP5D, DCPS ZDHHC20 1646/4885ZDHHC2 2407/4885TSHR 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.