Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547523 | 0.98 | PKM (0.71) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL11537146 | 0.98 | PKM (0.71) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL18380885 | 0.93 | PKM (0.58) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL11422598 | 0.93 | PKM (0.58) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL18388053 | 0.93 | PKM (0.58) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL11814905 | 0.86 | PKM (0.53) | PKMRAB9ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28798409 | 0.85 | PKM (0.68) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL27930078 | 0.83 | PKM (0.53) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL11811803 | 0.82 | PKM (0.52) | PKMEPHX2LMNAALDH1A1POLB | |
| SCHEMBL28207670 | 0.81 | PKM (0.68) | PKMRAB9ASMN1; SMN2EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797419-A | AGING RESISTANCE | WARNER-LAMBERT COMPANY (US) | 1989-01-10 | — | — | US | claimed |
| US-4797419-A | AGING RESISTANCE | WARNER-LAMBERT COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-3932658-A | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |