Indene

Indene

SCHEMBL1053919

C1=CCC=C1.C1=Cc2ccccc2C1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
PARP1 P09874 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL21494586 1.00 CA1 (0.47) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL28808888 0.98 CA1 (0.46) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL28135384 0.91 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL4444688 0.89 CA1 (0.52) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL29350094 0.89
Indene SCHEMBL8617 0.89
Indene SCHEMBL8336138 0.89 CA1 (0.55) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL23071394 0.86 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL2967405 0.86 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1
Indene SCHEMBL8971559 0.86 CA1 (0.53) CA1CA2CYP2D6CYP2C19PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0086947-A1 PPE composition containing impact modifier, flame retardant/plasticizer and melt viscosity reducer GENERAL ELECTRIC COMPANY (US) 1983-08-31 EP claimed
EP-0085850-A1 PPE composition containing impact modifier and melt viscosity reducer GENERAL ELECTRIC COMPANY (US) 1983-08-17 EP claimed
CN-108779135-B Metallocene compound, catalyst component and catalyst for olefin polymerization comprising the same, and process for producing olefin polymer using the same 日本聚乙烯株式会社 2021-09-07 CN disclosed
US-10995167-B2 Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the same, and method for producing olefin polymer using catalyst for olefin polymerization JAPAN POLYETHYLENE CORPORATION (JP) 2021-05-04 US disclosed
EP-3431483-B1 METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION CATALYST JAPAN POLYETHYLENE CORP (JP) 2021-03-03 EP disclosed
US-20190092887-A1 METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION JAPAN POLYETHYLENE CORPORATION (JP) 2019-03-28 US disclosed
EP-3431483-A1 METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST COMPONENT AND OLEFIN POLYMERIZATION CATALYST EACH COMPRISING SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING SAID OLEFIN POLYMERIZATION CATALYST Japan Polyethylene Corporation (JP) 2019-01-23 EP disclosed
CN-108779135-A Metallocene compound, the catalyst component for olefin comprising it and catalyst for olefines polymerizing and the method for producing olefin polymer using catalyst for olefines polymerizing 日本聚乙烯株式会社 2018-11-09 CN disclosed
CN-105985368-A Metallocene complex containing heteroatom pi-ligand, its preparation method, its catalyst system and application of catalyst system 中国石油天然气股份有限公司 2016-10-05 CN disclosed
CN-105985383-A metallocene complex containing heteroatom pi-ligand, its preparation method, its catalyst system and application of catalyst system 中国石油天然气股份有限公司 2016-10-05 CN disclosed
US-20120302713-A1 RETARDATION FILM, AND ORGANIC EL DISPLAY DEVICE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-11-29 US disclosed
CN-101512397-B Retardation film, and liquid crystal display device using the same NIPPON OIL CORP 2011-07-13 CN disclosed
US-7867581-B2 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2011-01-11 US disclosed
CN-101512397-A Retardation film, and liquid crystal display device using the same NIPPON OIL CORP (JP) 2009-08-19 CN disclosed
US-20090156770-A1 Retardation film and liquid crystal display device using the same NIPPON OIL CORPORATION (JP) 2009-06-18 US disclosed
CN-1414980-A Mixed metal alkoxide and cycloalkadienyl catalysts for preparing polyolefins UNION CARBIDE CHEM PLASTIC (US) 2003-04-30 CN disclosed
EP-0569249-B1 Ethylene/alpha-olefin copolymers NIPPON OIL CO LTD (JP) 1997-08-06 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed
EP-0086947-A1 PPE composition containing impact modifier, flame retardant/plasticizer and melt viscosity reducer GENERAL ELECTRIC COMPANY (US) 1983-08-31 EP disclosed
EP-0085850-A1 PPE composition containing impact modifier and melt viscosity reducer GENERAL ELECTRIC COMPANY (US) 1983-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092887-A1 METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION COG1, CPNE4, COG4 CA1 2513/4885CA2 4576/4885CYP2D6 613/4885
US-10995167-B2 Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the same, and method for producing olefin polymer using catalyst for olefin polymerization COG1, CPNE4, COG4 CA1 2513/4885CA2 4576/4885CYP2D6 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.