Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10539245 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5262223 | 0.88 | CYP2D6 (0.40) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5262226 | 0.88 | CYP2D6 (0.40) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29281063 | 0.87 | CYP2D6 (0.43) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30542821 | 0.86 | CYP2D6 (0.39) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26363230 | 0.86 | CYP2D6 (0.39) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1345404 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1345402 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8472008 | 0.82 | MAPT (0.41) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10541861 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP2D6SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870182-A | 4-Hydroxy-quinoline-3-carboxylic | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| US-4804760-A | Process for the preparation of 4-hydroxy-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| EP-0245690-A1 | Process for the preparation of 4-hydroxy-quinoline-3-carboxylic acids | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |