Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 9/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272865 | 0.84 | CNR2 (0.49) | CNR2HTR7CNR1 | |
| Hydrochloric Acid SCHEMBL7267283 | 0.83 | CNR2 (0.48) | CNR2HTR7CNR1 | |
| SCHEMBL10542753 | 0.80 | CNR2 (0.57) | KDM4EALDH1A1CNR2POLB | |
| SCHEMBL7265554 | 0.80 | CNR2 (0.49) | KDM4EALDH1A1SMN1; SMN2CNR2HTR7 | |
| SCHEMBL7057627 | 0.79 | CNR2 (0.49) | CNR2HTR7CNR1 | |
| SCHEMBL10540399 | 0.79 | POLB (0.54) | ALDH1A1CNR2POLB | |
| SCHEMBL7266996 | 0.75 | MEN1 (0.53) | CNR2POLB | |
| SCHEMBL7057530 | 0.74 | CNR2 (0.52) | CNR2POLBHTR7CNR1 | |
| SCHEMBL76649 | 0.73 | GAA (0.68) | KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10540522 | 0.73 | MEN1 (0.54) | CNR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808605-A | Tetrahydronaphthalene derivatives as calcium antagonists | HOFFMANN-LA ROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |