Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7267283 | 0.99 | CNR2 (0.48) | CNR2CNR1ABCB1HTR7 | |
| SCHEMBL10539289 | 0.84 | KDM4E (0.51) | CNR2CNR1HTR7 | |
| SCHEMBL7057627 | 0.82 | CNR2 (0.49) | CNR2CNR1ABCB1HTR7 | |
| SCHEMBL7272870 | 0.80 | CNR2 (0.49) | CNR2 | |
| SCHEMBL13354921 | 0.78 | CNR2 (0.53) | CNR2CNR1HTR7 | |
| SCHEMBL7274898 | 0.78 | TSHR (0.51) | — | |
| SCHEMBL7265554 | 0.78 | CNR2 (0.49) | CNR2CNR1HTR7 | |
| SCHEMBL7057530 | 0.77 | CNR2 (0.52) | CNR2CNR1HTR7 | |
| SCHEMBL7103505 | 0.76 | PAOX (0.53) | — | |
| SCHEMBL13588573 | 0.75 | CNR2 (0.72) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028991-C | Tetrahydronaphthalene derivatives | HOFFMANN LA ROCHE (CH) | 1995-06-21 | — | — | CN | disclosed |
| EP-0268148-B1 | TETRAHYDRONAPHTHALENE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| US-4808605-A | Tetrahydronaphthalene derivatives as calcium antagonists | HOFFMANN-LA ROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0268148-A1 | Tetrahydronaphthalene derivatives and medicaments containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| CN-87107875-A | TETRAHYDRONAPHTHALENE DERIVATIVES | — | 1988-05-25 | — | — | CN | disclosed |