Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL1559719 | 1.00 | TTR (0.43) | TTRTSHRKMT2AGAAMEN1 | |
| Ether SCHEMBL233512 | 1.00 | TTR (0.43) | TTRTSHRKMT2AGAAMEN1 | |
| Ether SCHEMBL368206 | 0.96 | — | — | |
| Ether SCHEMBL8643412 | 0.93 | — | — | |
| Dioxane SCHEMBL8034299 | 0.91 | ALDH1A1 (0.47) | TTRTSHRKMT2AGAAMEN1 | |
| Ether SCHEMBL12988654 | 0.90 | TSHR (0.34) | TTRTSHRKMT2AGAAMEN1 | |
| Dioxane SCHEMBL3113374 | 0.88 | ALDH1A1 (0.46) | TTRTSHRKMT2AGAAMEN1 | |
| Dioxane SCHEMBL22578249 | 0.88 | TSHR (0.35) | TTRTSHRKMT2AGAAMEN1 | |
| Ether SCHEMBL6934476 | 0.87 | TSHR (0.33) | TSHRKMT2AGAAMEN1ALDH1A1 | |
| Tetrahydrofuran SCHEMBL2114570 | 0.87 | ALDH1A1 (0.50) | TSHRKMT2AGAAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000811-B1 | Crown Ether Complexes and Methods for Poducing the Same | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2017-11-08 | — | — | EP | disclosed |
| EP-3000811-A1 | Crown ether complexes and methods for poducing the same | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2016-03-30 | — | — | EP | disclosed |
| US-4876381-A | Naphthalene derivatives possessing a retinoid-type action, processes for their preparation, and medicinal and cosmetic compositions containing these derivatives | L'OREAL (FR) | 1989-10-24 | — | — | US | disclosed |