Dioxane

Dioxane

SCHEMBL3113374

C1COCCO1.CCOCC.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.36
GAA P10253 3/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 3/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TTR P02766 1/20 0.33
RECQL P46063 1/20 0.32
RAB9A P51151 2/20 0.32
FKBP1A P62942 1/20 0.31
LMNA P02545 3/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PDK1 Q15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL1988246 0.97 ALDH1A1 (0.48) ALDH1A1TSHRKDM4EGAAKMT2A
Tetrahydrofuran SCHEMBL9066399 0.90 ALDH1A1 (0.42) ALDH1A1TSHRPOLBHTTL3MBTL1
Dioxane SCHEMBL4418046 0.89 ALDH1A1 (0.37) ALDH1A1TSHRKDM4EGAAPOLB
Ether SCHEMBL6810419 0.88 ALDH1A1 (0.43) ALDH1A1TSHRGAAKMT2AMEN1
Ether SCHEMBL233512 0.88 TTR (0.43) ALDH1A1TSHRGAAKMT2AMEN1
Ether SCHEMBL10539362 0.88 TTR (0.43) ALDH1A1TSHRGAAKMT2AMEN1
Dioxane SCHEMBL1559719 0.88 TTR (0.43) ALDH1A1TSHRGAAKMT2AMEN1
Ether SCHEMBL368206 0.85
Dioxane SCHEMBL5933613 0.84 ALDH1A1 (0.70) ALDH1A1TSHRKDM4EGAAKMT2A
Ether SCHEMBL8857934 0.84 ALDH1A1 (0.37) ALDH1A1TSHRPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2017310-B1 Ink jet printing ink containing thin aluminium effect pigments and method ECKART GMBH (DE) 2014-02-12 EP disclosed
US-8608843-B2 Pigment preparation and ink jet printing ink ECKART GMBH (DE) 2013-12-17 US disclosed
US-20130088553-A1 PIGMENT PREPARATION AND INK JET PRINTING INK ECKART GMBH (DE) 2013-04-11 US disclosed
US-8333832-B2 Pigment preparation and ink jet printing ink ECKART GMBH (DE) 2012-12-18 US disclosed
US-20120274714-A2 INK JETPRINTING INK CONTAINING THIN ALUMINIUM EFFECT PIGMENTS AND METHOD ECKART GMBH (DE) 2012-11-01 US disclosed
EP-2083052-B1 Pigment preparation and ink jet printing ink ECKART GMBH (DE) 2010-12-01 EP disclosed
US-20100279083-A1 PIGMENT PREPARATION AND INK JET PRINTING INK ECKART GMBH (DE) 2010-11-04 US disclosed
US-20100194836-A1 INK JET PRINTING INK CONTAINING THIN ALUMINIUM EFFECT PIGMENTS AND METHOD ECKART GMBH (DE) 2010-08-05 US disclosed
EP-2083052-A1 Pigment preparation and ink jet printing ink Eckart GmbH (DE) 2009-07-29 EP disclosed
WO-2009083176-A1 PIGMENT PREPARATION AND INK JET PRINTING INK ECKART GMBH (DE) 2009-07-09 WO disclosed
WO-2009010288-A2 INK JET PRINTING INK CONTAINING THIN ALUMINIUM EFFECT PIGMENTS AND METHOD ECKART GMBH (DE) 2009-01-22 WO disclosed
EP-2017310-A1 Ink jet printing ink containing thin aluminium effect pigments and method Eckart GmbH (DE) 2009-01-21 EP disclosed
EP-0159882-B1 POLYESTER FIBERS TEIJIN LIMITED (JP) 1989-07-12 EP disclosed
US-4621020-A PAPERMAKING TELJIN LTD. (JP) 1986-11-04 US disclosed
EP-0159882-A1 Polyester fibers TEIJIN LIMITED (JP) 1985-10-30 EP disclosed