Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536184 | 0.88 | GRM2 (0.33) | TYRGRM2CNR2 | |
| SCHEMBL3266092 | 0.79 | KDM4E (0.32) | ALDH1A1KDM4E | |
| SCHEMBL10538607 | 0.78 | ALDH1A1 (0.39) | ALDH1A1POLBKMT2ATLR8NPSR1 | |
| SCHEMBL10536006 | 0.74 | CYP1A2 (0.37) | ALDH1A1POLBKMT2ATLR8NPSR1 | |
| SCHEMBL1925550 | 0.73 | TLR8 (0.40) | ALDH1A1POLBKMT2ATLR8NPSR1 | |
| SCHEMBL10536070 | 0.73 | CNR1 (0.36) | ALDH1A1POLBKMT2ATLR8NPSR1 | |
| Bromide SCHEMBL29212810 | 0.72 | NPC1 (0.43) | ALDH1A1POLBKMT2ATLR8NPSR1 | |
| SCHEMBL14625802 | 0.72 | CRBN (0.33) | KDM4EPGR | |
| SCHEMBL30982990 | 0.71 | KDM4E (0.42) | TLR8LMNAHTTTYRKDM4E | |
| SCHEMBL30982374 | 0.71 | KDM4E (0.42) | TLR8LMNAHTTTYRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826869-A | GLAUCOMA | SYNTEX (U.S.A.) INC. (US) | 1989-05-02 | — | — | US | disclosed |