Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10539640 | 0.79 | ALDH1A1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL2969372 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1MAPK1GABRA1GABRB2 | |
| SCHEMBL2962188 | 0.74 | GABRA1 (0.34) | KDM4EALDH1A1MAPK1GABRA1GABRB2 | |
| SCHEMBL3344965 | 0.73 | KDM4E (0.30) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL868431 | 0.73 | KDM4E (0.47) | KDM4EGABRA1GABRB2 | |
| SCHEMBL23839890 | 0.70 | GABRA1 (0.45) | KDM4EALDH1A1MAPK1GABRA1GABRB2 | |
| SCHEMBL12727081 | 0.69 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL11400414 | 0.68 | DRD3 (0.33) | — | |
| SCHEMBL4990189 | 0.66 | PARP1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL11650532 | 0.65 | PGR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220562-A1 | Anti-Viral Compounds | Abbott Labaoratories (US) | 2012-08-30 | — | — | US | disclosed |
| US-20120004196-A1 | Anti-Viral Compounds | Abbott Labaoratories (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220562-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | KDM4E 2318/4885ALDH1A1 2858/4885MAPK1 2093/4885 |
| US-20120004196-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | KDM4E 2318/4885ALDH1A1 2858/4885MAPK1 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.