Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | PYGL | P06737 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10541801 | 0.92 | KMT2A (0.50) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10542037 | 0.91 | CYP2D6 (0.55) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10537786 | 0.86 | MAPT (0.67) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10540683 | 0.85 | MAPT (0.55) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10542205 | 0.83 | POLB (0.60) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10541780 | 0.83 | CYP2D6 (0.54) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10542188 | 0.81 | PYGL (0.48) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10540768 | 0.81 | KMT2A (0.47) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL10540979 | 0.81 | TSHR (0.59) | MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL10539974 | 0.81 | MAPT (0.56) | MAPTALDH1A1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797387-A | ANALGESICS, ANTIEMETICS | BEECHAM GROUP, P.L.C. (GB) | 1989-01-10 | — | — | US | disclosed |