Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29648775 | 0.79 | CYP3A4 (0.49) | TDP1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL160585 | 0.79 | CYP3A4 (0.49) | TDP1CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1191181 | 0.79 | CYP1A2 (0.53) | KMT2AMEN1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3652399 | 0.79 | CYP3A4 (0.37) | TTRTDP1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL673041 | 0.78 | KMT2A (0.44) | TDP1KMT2ACYP3A4ALDH1A1HPGD | |
| SCHEMBL11849090 | 0.76 | CYP3A4 (0.46) | TDP1CYP3A4ALDH1A1HPGDTSHR | |
| SCHEMBL10906029 | 0.74 | CYP3A4 (0.45) | TTRTDP1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL166668 | 0.74 | CYP3A4 (0.49) | TTRTDP1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL42899 | 0.72 | CYP3A4 (0.43) | TDP1KMT2ACYP3A4ALDH1A1HPGD | |
| SCHEMBL2181422 | 0.72 | HTR2A (0.46) | TDP1KMT2AMEN1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308746-A2 | N-benzoyl-N-(2,3-dichloro-4-phenoxy)-phenyl ureas | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | claimed |
| US-4880837-A | INSECTICIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | disclosed |
| EP-0308746-A2 | N-benzoyl-N-(2,3-dichloro-4-phenoxy)-phenyl ureas | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | disclosed |