Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369946 | 0.91 | GRM5 (0.46) | GRM5CYP19A1MAPK14CYP1A2CYP3A4 | |
| SCHEMBL2614974 | 0.87 | CCR1 (0.58) | GRM5CCR1CCR8TGFBR1MGAM | |
| SCHEMBL8951980 | 0.84 | CCR1 (0.47) | GRM5CCR1CCR8MAPK14TGFBR1 | |
| SCHEMBL10940020 | 0.80 | CYP19A1 (0.56) | GRM5CYP19A1MAPK14CYP1A2CYP3A4 | |
| SCHEMBL10537438 | 0.80 | TGFBR1 (0.46) | GRM5CCR1CCR8MAPK14TGFBR1 | |
| SCHEMBL4542421 | 0.79 | GRM5 (0.55) | GRM5CCR1CCR8MAPK14TGFBR1 | |
| Methyl Alcohol SCHEMBL10711710 | 0.79 | MAPK14 (0.53) | GRM5CYP19A1MAPK14CYP1A2CYP3A4 | |
| SCHEMBL10540409 | 0.79 | HSP90AA1 (0.54) | GRM5CYP19A1CCR1CCR8MAPK14 | |
| SCHEMBL15470589 | 0.78 | CCR1 (0.60) | GRM5CCR1CCR8MAPK14TGFBR1 | |
| SCHEMBL10539132 | 0.78 | CYP2A6 (0.53) | GRM5CCR1CCR8MAPK14TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873248-A | Pyridinylpyrimidines having fungicidal activity | SUMITOMO CHEMICAL CO., LTD. (JP) | 1989-10-10 | — | — | US | claimed |
| EP-0270362-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | claimed |