Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485496 | 0.91 | TRPM8 (0.44) | TRPM8CYP3A4LMNATDP1TEAD1 | |
| Hydrochloric Acid SCHEMBL2485467 | 0.89 | TRPM8 (0.43) | TRPM8CYP3A4LMNATDP1TEAD1 | |
| SCHEMBL3948272 | 0.84 | NOTUM (0.50) | TRPM8CYP3A4LMNATDP1TEAD1 | |
| SCHEMBL1028025 | 0.84 | TDP1 (0.56) | TRPM8CYP3A4LMNATDP1TEAD1 | |
| SCHEMBL9780053 | 0.81 | TRPM8 (0.45) | TRPM8CYP3A4LMNATDP1TEAD1 | |
| SCHEMBL28635231 | 0.79 | CYP3A4 (0.47) | TRPM8CYP3A4LMNATDP1TEAD1 | |
| SCHEMBL4646824 | 0.78 | AKR1B1 (0.47) | TDP1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL8922646 | 0.77 | TRPM8 (0.53) | TRPM8CYP3A4LMNATEAD1TP53 | |
| SCHEMBL9134325 | 0.75 | TRPM8 (0.51) | TRPM8CYP3A4LMNATEAD1TP53 | |
| SCHEMBL7196096 | 0.74 | TRPM8 (0.40) | TRPM8CYP3A4LMNATDP1TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4846877-A | CYCLIC DIMERS OF PHENYLGLYCINE | TEIJIN LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4772314-A | PHENYLGLYCINES, MONOMERIC | TEIJIN LIMITED (JP) | 1988-09-20 | — | — | US | disclosed |
| US-4069385-A | FROM AN OLEFIN AND AN ORGANIC PEROXIDE WITH COPPER-SCHIFF BASE COMPEX AS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-17 | — | — | US | disclosed |