Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134325 | 0.85 | TRPM8 (0.51) | TRPM8CYP3A4LMNAALDH1A1TP53 | |
| SCHEMBL7867200 | 0.84 | CYP3A4 (0.61) | TRPM8CYP3A4LMNAALDH1A1TP53 | |
| SCHEMBL6907834 | 0.83 | OPRM1 (0.48) | ALDH1A1HPGDOPRM1 | |
| SCHEMBL6470937 | 0.79 | ALDH1A1 (0.55) | CYP3A4ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL4150527 | 0.78 | ALDH1A1 (0.59) | TRPM8CYP3A4LMNAALDH1A1TP53 | |
| SCHEMBL9593362 | 0.78 | CYP3A4 (0.50) | TRPM8CYP3A4LMNAALDH1A1TP53 | |
| SCHEMBL6904263 | 0.77 | PTGS2 (0.44) | LMNAALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL9134227 | 0.77 | CA12 (0.53) | TRPM8ALDH1A1MEN1KMT2A | |
| SCHEMBL23031991 | 0.77 | LMNA (0.49) | TRPM8CYP3A4LMNAALDH1A1TP53 | |
| SCHEMBL1028025 | 0.77 | TDP1 (0.56) | TRPM8CYP3A4LMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |