Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546300 | 0.79 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL6368944 | 0.76 | DRD4 (0.45) | — | |
| SCHEMBL10544630 | 0.74 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL9719789 | 0.71 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL9865828 | 0.71 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL10547998 | 0.70 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2GPBAR1PDE10AFFAR1 | |
| SCHEMBL10549147 | 0.69 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL6583310 | 0.69 | CYSLTR1 (0.78) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL10922049 | 0.69 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1PDE10AALOX5 | |
| SCHEMBL10545819 | 0.69 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |