Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329125 | 0.84 | KMT2A (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10543980 | 0.82 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL926032 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10541412 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGUSBCOMT | |
| SCHEMBL538577 | 0.79 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31255110 | 0.78 | MAPT (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL26632758 | 0.78 | MAPT (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10565234 | 0.78 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6732648 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL6201155 | 0.76 | THRB (0.45) | ALDH1A1MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870182-A | 4-Hydroxy-quinoline-3-carboxylic | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| US-4804760-A | Process for the preparation of 4-hydroxy-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |