Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | CPT2 | P23786 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 1/20 | 0.45 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526841 | 0.84 | ALDH1A1 (0.60) | HTTLMNAMAPTKMT2AKDM4E | |
| SCHEMBL3249787 | 0.84 | ALDH1A1 (0.53) | HTTLMNAMAPTKMT2AKDM4E | |
| SCHEMBL7532986 | 0.81 | ADRB3 (0.48) | HTTLMNAMAPTKMT2AKDM4E | |
| SCHEMBL14389382 | 0.81 | KDM4E (0.70) | HTTLMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14038485 | 0.80 | ALDH1A1 (0.47) | HTTLMNAMAPTKMT2AKDM4E | |
| SCHEMBL13719670 | 0.80 | KDM4E (0.46) | HTTLMNAMAPTKMT2AKDM4E | |
| SCHEMBL1120778 | 0.79 | ADRB3 (0.46) | HTTLMNAMAPTKMT2AKDM4E | |
| SCHEMBL4161973 | 0.76 | MEN1 (0.61) | HTTMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL3637730 | 0.74 | KDM4E (0.40) | HTTLMNAMAPTKMT2AKDM4E | |
| Diapamide SCHEMBL119354 | 0.73 | GSTO1 (0.54) | HTTLMNAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855289-A | Combination of two active substances | WESTER PER O (SE) | 1989-08-08 | — | — | US | disclosed |